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Look for a purity rating of 98% or higher

This protective effect was similar in those with and without a history of a previous cardiovascular event

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The trial enrolled adults with obesity (or overweight with at least one weight-related condition) and randomized participants across several retatrutide dose levels or placebo over a 48-week period

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Patients experiencing significant gastrointestinal side effects might benefit from dose reduction before stopping entirely, and those with type 2 diabetes require transition planning to alternative glucose-lowering therapies