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It stabilizes delicate mitochondrial membranes, significantly reduces the generation of destructive reactive oxygen species (ROS), and protects the cell from ferroptosis, a severe form of iron-dependent cell death

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In the previous century, the underlined function of TMAO was the stabilization of proteins against various environmental stress factors, including high hydrostatic pressure [73]

32 Nucleophilic Substitution Reaction of the Hydroxyl Group on L-Carnitine with Propionyl Chloride The hydroxyl group on L-carnitine can also react with nitric acid to form organic nitrate salts

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Journal of pain and symptom management , 32 (6), 551-559