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One study showed that 45% of the people who took phentermine lost 5% or more of their body weight in a little over a year

doi: 10.1038/s41591-022-01707-4

Clinicians should also use caution in patients with conditions such as gastroparesis, pancreatitis, gallbladder disease, renal failure or eating disorders

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FASEB J 34(5):69656983 Kim J et al (2021) Donepezil regulates LPS and A-stimulated neuroinflammation through MAPK/NLRP3 inflammasome/STAT3 signaling