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In clinical studies, some patients have lost up to 20% of their body weight using Tirzepatide

However, Mounjaro is FDA-approved for managing type 2 diabetes, while Zepbound is approved for helping adults with obesity, or those overweight with at least one weight-related health condition such as hypertension or high cholesterol, in weight management

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Potent body weight loss, and therapeutic efficacy in a NASH animal model by a novel long-acting GLP-1/GIP/glucagon tri-agonist (HM15211)

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The dose was then escalated to the full therapeutic dose of 1 mg once weekly during the third and fourth months