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P.et al (2018)

Melanocytes are neural-crest-derived cells that reside in the basal epithelial layer of the skin and oral mucosa

However, FDA approved (and insurance covered) estradiol patches are also composed of 17-beta estradiol which is the same molecular structure as the estrogen produced by your ovaries and derived from plants

It causes inflammation in major organs and tissues the skin, kidneys and joints but also the heart and brain in the cardiovascular and nervous systems (x)

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