Studied in models involving cellular repair signaling, tissue remodeling, and recovery-associated pathways
In the SURMOUNT clinical trial program for obesity, participants achieved average weight loss of 15-21% of body weight depending on dose, significantly exceeding results with diet and exercise alone or other available pharmacotherapies
The thickened bursa sac is removed, and the skin is repaired with stitches
This can lead to unnecessary dose escalation that causes problems when you eventually switch to a fresh, full-potency vial
For patients already meeting indications for use of a GLP-1 drug based on metabolic factors, its potential role in lowering uveitis risk could be an added consideration when selecting antihyperglycemic therapy. 1 While these possibilities are positive advancements, a commentary on the study, also published yesterday in JAMA Ophthalmology , provides some potential limitations to keep in mind when interpreting conclusions
Flammer J, Haefliger IO, Orgul S, Resink T