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No, the volume of the lyophilized powder itself is negligible

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Bull Exp Biol Med 2006;141:3903

Each 20mg vial contains 10mg of Semax and 10mg of Selank as a co-lyophilized powder, allowing investigators to evaluate the combined activity of two complementary neuroactive sequences in a single preparation

1000 mcg (as Pentadeca Short Chain Amino Acids) Other Ingredients: Water, glycerin, ethanol, highly purified phospholipids, tocofersolan, natural mixed tocopherols If pregnant or breast feeding, consult your healthcare practitioner before use

Afterwards, gently swirl or roll the vial between your hands