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Our results demonstrate that the core clock protein BMAL1 regulates astrocyte activation and function in vivo, elucidating a novel mechanism by which the circadian clock could influence many aspects of brain function and neurologic disease.

Neuroscience 151:10531065 Walters JL, Paule MG (2017) Review of preclinical studies on pediatric general anesthesia-induced developmental neurotoxicity

The aforementioned small molecule inhibitors targeting xCT could induce ferroptosis in tumor cells through inhibition of xCT activity

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Among the human studies, exenatide showed the most robust efficacy in enhancing abstinence from nicotine, as well as reducing craving and weight gain

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