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He warned that GLP-1 medications can also have more serious effects, and patients should not use them lightly

Even a few hours at 70F can begin breaking down the active ingredient, though the pen may still appear normal to the naked eye

Diabetes Care 38(9):16871693

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If passed, TROA would: Permanently allow Medicare Part D to cover FDA-approved anti-obesity medications Expand Medicare Part B coverage of intensive behavioral therapy for obesity to include a wider range of providers (not just primary care physicians) However, in April 2025, CMS announced it would not include Medicare Part D coverage of obesity drugs in its rule changes for 2026, stating the proposal was "not appropriate at this time." That decision pushed the issue back to Congress, where the TROA remains under consideration

Even if the appearance is normal, prolonged heat exposure may reduce potency