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Limitations Although LGE is useful for reproducible assessment of myocardial scarring and replacement fibrosis, it is limited in its accuracy in the assessment of diffuse fibrosis
However, a notable side effect was observed: MT-II-treated normal C57BL/6J mice exhibited significant weight loss, with their average weight decreasing from a baseline of 30.9 1.4 grams to 26.5 1.7 grams after the 14-day treatment course, a change not seen in vehicle-treated controls
Given its potent anti-inflammatory and prebiotic properties, researchers developed a PIP-loaded CS-modified poly(lactic-co-glycolic acid) (PLGA) nanoparticle (CS-PIPP)