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Cani PD, Amar J, Iglesias MA, Poggi M, Knauf C, Bastelica D, et al

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(June 1, 2006)

In rat fertility studies with oral gavage doses of 125, 250, and 1000 mg/kg, males were treated for 4 weeks prior to mating, during mating, up to scheduled termination (approximately 8 weeks total), and females were treated 2 weeks prior to mating through gestation day 7