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Glutathione: The Skin Brightening Antioxidant Why It Works Glutathione is an antioxidant that interferes with the synthesis of melanin in the skin and, in fact, drives the conversion to production of the lighter-colored (pheomelanin) versus the darker-colored (eumelanin) types of melanin, it combats reactive species in the skin, thereby putting a damper on hyperpigmentation

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However, they should not be viewed as substitutes for evidence-based HF therapies, and their role in established HFrEF remains less certain [18, 19, 22, 48]

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Methods In this retrospective cohort study, 125 474 adults with overweight or obesity newly initiated treatment with a dual-labeled GLP-1 RA (liraglutide, semaglutide, or tirzepatide) between January 1, 2018, and December 31, 2023, with a baseline body mass index of 27 or more, an available weight measurement within 60 days before initiation, and regular care in the year before initiation were identified using electronic health record data from a collective of US health care systems

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