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Potential limitations of both studies include the use of a single dose rather than multiple doses of cagrilintide and the use of doses (0.6 mg in the renal impairment study and 0.9 mg in the hepatic impairment study) lower than the 2.4 mg dose being evaluated in clinical development

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Common causesinclude: -Polypharmacy (especially in elderly patients) Over-the-counter drugs Herbal supplements and food interactions CYP450 enzyme interactions are among the most clinically significant for example, grapefruit juice inhibiting CYP3A4

10.3390/ijms222212143 286 MartelJ.ChangS

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*Allura AC red, cochineal red A, quinoline yellow may have a detrimental effect on activity and attention in children