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Discussion Among semaglutide users with T2D who achieved HbA1c and weight loss goals, this real-world analysis observed an association between semaglutide use and subsequent improvements across multiple CKM domains, including significant reductions in atherogenic lipids and blood pressure, meaningful decreases in UACR with largely stable eGFR, and lower MACE rates

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Future Developments: Higher Dose Tablets In addition to the approved tablet strengths, Novo Nordisk has filed a supplemental drug application for a 25 mg Ozempic tablet for adults with type 2 diabetes

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We thank our Data and Safety Monitoring Committee, our TSC and Trial Management Group members, and our patient and public involvement and engagement representatives who reviewed the trial protocol and participated in our TSC and Monitoring Committees