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A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone

Proposed mechanisms include indirect effects via weight loss and reduced inflammation, though no direct electrophysiological action on atrial tissue has been established

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Last year, for example, American researchers demonstrated that alpha lipoic acid (ALA) supplementation in older racehorses reduced the oxidative stress burden even under light training loads (4) , while a number of other animal studies have shown that acetyl L-carnitine (ALC)/ALA supplementation reduces oxidative stress and improves mitochondrial function in a number of tissues, including brain, muscle and heart

They show promise in immunomodulation, regeneration, drug delivery, and aesthetics

10.1038/ng1297-491 9 DonatoL.AlibrandiS.ScimoneC.CastagnettiA.RaoG.SidotiA.et al (2021)