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GLP-1/GLP-1R enhances insulin-promoting factor-1 (PDX-1) responsiveness via the epidermal growth factor receptor (EGFR)/phosphoinositide-3-kinase (PI3K)/protein kinase B (AKT/PKB)/fork head box protein O1 (FOXO1) signaling pathway, thereby maintaining -cell morphological function and promoting the conversion of non- cells to cells

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Rom J Intern Med (2019) 57:23340

Comparative effects of proximal and distal small intestinal glucose on glycaemia, incretin hormone secretion and incretin effect in healthy males

GLP-1 receptor agonists primarily work by slowing down gastric emptyingthe rate at which food leaves your stomachand signaling the brain that you are full