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Chronic altitude sickness CMS The prevalence of CMS varies by altitude, lung disease, sex, age, sleep apnea, obesity, and genetic factors

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27 The incorporation of polyunsaturated fatty acids (PUFAs) into membrane lipids first requires the activation of the free fatty acids into PUFA-CoAs by acyl-CoA synthetase long chain family member 4 (ACSL4) and incorporation of the PUFA-CoA into lipids by lysophosphatidylcholine acyltransferase 3 (LPCAT3)