According to the American Diabetes Association's Standards of Medical Care in Diabetes, proper injection technique and systematic site rotation are essential for optimal medication absorption and to prevent lipohypertrophy (thickening of fatty tissue) or lipoatrophy (loss of fatty tissue) at injection sites
Cahn A, Cefalu WT (2016) Clinical considerations for use of initial combination therapy in type 2 diabetes
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Do I add different medications
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