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Addition of wortmannin, a biochemical inhibitor of AKT signaling that is central to insulin-mediated stimulation of glucose transport 52 effectively blocked insulin-stimulated glucose uptake in muscle tissue

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Deficiencies in thiamine result in neurological, muscular, and cardiac symptoms, and can occur in as little as 18 days of total dietary depletion

doi: 10.3892/etm.2022.11328