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For Fisher exact test comparing CVD phenotypes between GLP1RA and SGLT2i we extracted related gene lists from Malacards database ( MI, HF, Ischemic stroke, Heart disease, Hypertension, Congestive HF, T2DM
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In multiple oxidative stress models of retinal degeneration, elevated GPX4 expression has been shown to protect photoreceptors and RPECs, suggesting that increasing GPX4 expression may represent a potential gene therapy approach for patients with AMD (47, 48)
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Long pentraxin PTX3 upregulates tissue factor expression in human endothelial cells: a novel link between vascular inflammation and clotting activation
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