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But Joel Dave, head of the division of endocrinology at UCT, cautions that Ozempic only works while you take it and doesnt address the underlying reasons for weight gain so people need to take it lifelong, if they want to maintain their weight loss

Start with alternate-day applications

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Use healthy oils for salads and for cooking

It is indicated for long-term use, but its safety and effectiveness over periods longer than two years have not been established

Due to their mode of action being the direct modification, upregulation, or inhibition of transcripts (Juliano and Carver, 2015