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However, since whole cell lysates have been utilized successfully in previous studies [10, 37, 56], the possibility that the observed changes in enzyme activity are true physiological responses to nitrogen availability should not be disregarded

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Furthermore, while tumor cell density modulates ferroptosis via the TAZEMP1NOX4 axis (232), the upstream triggers of this axis in RCC (e.g., hypoxia and ECM stiffness) and its interplay with other TME signals (e.g., cytokines and growth factors) are not elucidated

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Transcription of the gene for a pepsinogen, PEP1, is regulated by white-opaque switching in Candida albicans

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