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Ample evidence has proved that BRAF and MEK inhibitors could promote the priming and function of tumor infiltration T cells, facilitate antigen presentation and modulate the tumor environment to be harmful for tumor cells in mouse model and in vitro

PLoS ONE 19(9):e0308500 Zhang H et al (2024) ZDHHC20-mediated S-palmitoylation of YTHDF3 stabilizes MYC mRNA to promote pancreatic cancer progression

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This subtype frequently overlaps with other autoimmune conditions like Ehlers-Danlos Syndrome (EDS), Sjgrens syndrome, and lupus

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