This level of control is harder to achieve with oral supplements, where absorption can be influenced by factors like food intake and gastrointestinal health
As you achieve the significant 20.9% body weight reduction seen in the SURMOUNT-1 clinical trial, your physiological requirements for hormone replacement naturally shift
This gradual approach is designed to support long-term weight management by allowing the body to adapt, minimizing the severity of gastrointestinal effects during the early weeks of appetite control
However, high fluid intake is not always healthy or harmless
Most users experience mild to moderate gastrointestinal issues, such as nausea, diarrhea, or constipation
According to NICE Technology Appraisal 875, Wegovy is recommended for use within the NHS for adults with a BMI of at least 35 kg/m and at least one weight-related comorbidity, or a BMI of at least 30 kg/m with type 2 diabetes, when provided through specialist weight management services