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2.2.2 Solvent selection Following a preliminary experiment, dimethylformamide (DMF), PEG400, glycerol formal (GF), -pyrrolidone (-P) and propylene glycol (PG) were selected as potential solvents

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Hepatocyte models have been used to investigate effects on glucose output and lipogenic gene expression, while 3T3-L1 and primary adipocyte cultures have characterised effects on lipolysis, GLUT4 translocation, and adipokine secretion

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Clinical trials show that improper dosing can lead to severe gastrointestinal distress, hypoglycemia, and electrolyte imbalances