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Regarding hematological parameters and inflammatory mediators, mice from saline-CLP group showed a significant augment in the number of circulating total leukocytes (Figure 2C), monocytes (Figure 2D), neutrophils (Figure 2E), and platelets (Figure 2F)

3.2.2.2 Resveratrol Besides promoting mitochondrial biogenesis, resveratrol also attenuates mitochondrial dysfunction and restores renal function via other multiple mechanisms

Molecular Basis of Disease, 1866(6), 165741

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IGF-1 LR3 primarily exerts its effects through activation of the IGF-1 receptor (IGF-1R), a transmembrane tyrosine kinase receptor expressed in muscle, bone, connective tissue, and various other cell types