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Accurate communication about NAD+ research is essential, given the molecules biological importance and the sensitivity of cancer discussions

The Gsta4 effect on apoptosis during adult OL differentiation was corroborated in vivo in both lysolecithin-induced demyelination and experimental autoimmune encephalomyelitis models, where Casp8 activity was reduced in Gsta4-overexpressing OLs

doi: 10.1016/j.ijbiomac.2019.08.138 178 HuaSMarksESchneiderJJKeelyS

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There is the concern about false positives and false negatives when it comes to these screening modalities

Eligible interventions include small molecules (including repurposed drugs), ATMPs (with GMPvalidated manufacturing appropriate for Phase I/II), biologics/new biological entities, and repurposed biologics