NAC (2 mM, Sigma-Aldrich, A7250)
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Interestingly, capacity of OPCs to remyelinate is also strongly reduced with ageing 37,38,39 , even if a link with cellular stress has not been proven
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The result is probably barely noticeable to anyone else, but it has really helped improve my confidence
AGEs are final, permanent products of glycation that can modify the physicochemical properties of proteins, increase their resistance to proteolysis, and interact with RAGE receptors, causing oxidative stress and an inflammatory response 57