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However, these studies excluded individuals with a history of major depression or psychiatric diseases and reported no significant differences in psychiatric outcomes between liraglutide and placebo groups

Lean mass dropped by around 9.7%, but fat mass fell by 19.3%, and the proportion of lean mass in the body increased by about 3 percentage points

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Men taking other medications should disclose their full medication list to ensure semaglutide does not alter absorption or efficacy of other drugsthough direct reproductive toxicity is not a documented concern with GLP-1 agents

For a deeper treatment of the mechanism, see our clinical overview of semaglutide and the broader class of GLP-1 medications for weight loss

Al principio, estos medicamentos solo se usaban en casos concretos de diabetes, pero ahora se usan tambin para tratar la obesidad