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They are not approved for type 1 diabetes because they depend on residual beta cell function

Topiramate, an anticonvulsant approved for weight reduction in combination products, is sometimes considered alongside GLP-1 drugs like Ozempic (semaglutide)

Moreover, although we were able to assess overall mortality, we were unable to assess disease-specific mortality, which could provide clarity on the cause of death

Appetite-Modulating Activity Activation of MC4R modulates appetite-regulation pathways, with potential relevance for some patients in carefully selected contexts

But there's still meaningful work ahead

Tell a doctor, pharmacist or nurse if: the symptoms worsen or persist during the use of the medicinal product