In particular, upon administration in mice, only the mono-glutathionylated adducts were not toxic to kidneys, while a correlation was recorded between the number of glutathione substitutions and the nephrotoxicity observed [83]
As a result, RAE was introduced and partially replaced the old unit depending on the referring health institution: 1 g RAE equals 1 g retinol, 2 g supplemental -carotene, 12 g dietary -carotene, or 24 g dietary -carotene or -cryptoxanthin, whereas 1 g RE required only 6 g -carotene [82,83,84,85]
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[DOI] [PMC free article] [PubMed] [Google Scholar] 105.World Health Organization
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