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doi: 10.1097/01.ju.0000135918.00761.8a

Beyond oxidative damage, alpha-synuclein ( -syn) aggregation is a central pathological hallmark of PD, as it is the major component of Lewy bodiesabnormal deposits of proteins found in the brains of patients with PD (Paulkas et al., 2024)

For ibuprofen specifically, taking it with a full glass of water and food may partly offset mucosal contact risk, but it does not eliminate delayed absorption or renal effects

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Subjects without NSAID treatment listing in the SD might include subjects that used NSAIDs only for a short time and did not inform their attending physician