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Lpez-Otn C, Blasco MA, Partridge L, Serrano M, Kroemer G

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318,319,320 Furthermore, stability can be improved without compromising drug activity by optimizing the number and modification positions of 2-F and 2-OME groups on both strands of double-stranded siRNA, leading to substantial efficacy improvements

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[DOI] [PubMed] [Google Scholar] 56.Malo C, Grundin J, Morrell JM, Skidmore JA