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Images were captured on a Zeiss Axioplan 2 Imaging microscope equipped with an AxioCam MRm camera using AxioVision 4.6 software (Zeiss), or confocal microscope imaging was performed on a Zeiss LSM 800 microscope

However, the third trimester of gestation is the period when ewes require high energy and nutrients due to the rapidly developing fetus

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Higher ("pharmacologic") doses are required to produce significant acceleration of growth in these conditions, producing blood levels well above normal ("physiologic")

European Journal of Pharmaceutics and Biopharmaceutics 98 , 4756, (2016)

This supports mitochondrial energy production, which becomes more important when calories are lower