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In rats, feeding activity and food intake decreased following intracerebroventricular injection of GLP-1, an effect counteracted by co-administration of a GLP-1 receptor antagonist (71, 72), suggesting central GLP-1 as a potent inhibitor of feeding

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Qin W, Yang J, Ni Y, et al

About the practical aspects: "What is the titration schedule, and how quickly will we increase the dose?" "How should I handle injection technique and site selection ?" "What is the best time of day to take this medication?" "How should I store the medication ?" "What happens if I miss a dose or need to adjust timing ?" Practical questions demonstrate that you are already thinking about adherence and implementation, not just acquisition

These findings align with larger clinical trials

Polyzos, S