ZhangYQuZLuTShaoXCaiMDilimulatiDet al
Despite promising in vitro and in vivo efficacy, validation remains limited to two cell lines and animal models
These findings indicate that GDF8 and ActA are key regulators of muscle loss during caloric restriction, and that blocking these negative regulators of muscle mass during the treatment of obesity with GLP-1 RAs could provide profound and wide-ranging benefits
doi: 10.2991/jegh.k.191028.001 2 BommerCSagalovaVHeesemannEManne-GoehlerJAtunRBrnighausenTet al
Montero R, Grazina M, Lpez-Gallardo E, Montoya J, Briones P, Navarro-Sastre A, et al
If youve struggled with fad diets or yo-yo weight loss, GLP-1 therapy could help you finally achieve your goals