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Patients with T2D with stable CAD presented an improvement in endothelial function expressed by an increase in flow-mediated vasodilation of the brachial artery, independent of changes in systolic and diastolic blood pressure during a hyperinsulinemic clamp in response to GLP-1 [35]

However, providers may prescribe it off-label for non-HIV patients with documented GH-axis deficiency and visceral fat excess

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