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Experimental models have evaluated it for cytoprotective and regenerative activities across gastrointestinal mucosa, tendons, ligaments, muscles, bone, nervous tissue, and vascular endothelium

To achieve equivalent systemic exposure, oral protocols typically use 100150mg doses to compensate for the reduced absorption

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This is because there are few vegan foods that contain B12 and also because the body finds it significantly more difficult to absorb B12 from the few vegan sources that have it

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This signals the pancreas to relax insulin after eating and signals the liver to decrease the output of glucose