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In that regard, actual market dominance appears to be significantly driven by simplicity of use, dosing schedule, injection site discomfort, robust efficacy, indication and contraindication in certain subpopulations, and low side-effect profile along with non-scientific factors, such as first-to-market, size and experience of the companys diabetes sales force, negotiated pricing and reimbursement agreement, geographic areas of regulatory approvals and patent exclusivity
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Among the most significant of these downstream effects are severe gut dysfunction, microbiome imbalances, and systemic inflammation