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Patients who may particularly benefit from GLP-1 receptor agonists include those with type 2 diabetes and established cardiovascular disease, obesity, or chronic kidney disease (where SGLT2 inhibitors are not suitable or as additional therapy)

What Happens Next Bofanglutide's Phase 2b data will need to be followed by Phase 3 trials likely in multiple global populations before any regulatory submission could proceed

R package version 3.1163 (2023)

Neuroanatomy of melanocortin-4 receptor pathway in the mouse brain

It plays a crucial role in energy production & brain function

The bottom line: the supply crunch is easing, but the arms race in manufacturing is just getting started