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At the molecular level, glutathione protects the delicate protein complexes of the mitochondrial electron transport chain (ETC)

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Beyond its direct antioxidant capabilities, intracellular glutathione is also essential for maintaining the optimal function of other critical antioxidants in the body

( D ) Binding curves and ( E ) calculated dissociation constants (Kd) under: control (black), 17 nM Sororin-12A (orange) and 17 nM each Sororin-12A and RSMC (yellow)

Lysates were clarified by centrifugation at 10,000 g at 4 C for 10 min, and the resulting supernatant was incubated with 1 ml of Glutathione Sepharose 4B beads (Cytiva, GE17- 0756-01) for 1 h at 4 C

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