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(iv) the ENS and vagus nerve connecting to (v) central autonomic circuits and HPA stress pathways

674 In a TBI mouse model, HBED treatment can reduce microglia proliferation and aquaporin 4 expression, thereby alleviating secondary injury in the cortical region after TBI and improving motor function in mice

Tung MC, Chang GR, Tu MY, Fan HC, Yen CC, Cidem A, Chen IC, Chen CM

J Proteomics (2017) 156:94103

But for some, obesity is a greater health risk than the medication itself

BMS has multiple combination regimens approved or in late-stage development, including nivolumab plus relatlimab (Opdualag) and nivolumab plus ipilimumab (Opdivo Yervoy), each carrying independent IP