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At 6 h after treatment, the decrease in ATP levels was not significant

Based on these observations, an ADC conjugated to duocarmycin through a cleavable enzymatic linker was designed against the B2M protein and used as a senolytic therapy

The method of embodiments39 or 40, wherein each medium chain fatty acid independently comprises 6 to 12 carbon atoms in the carbon chain

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This also helps in removing harmful toxins and free radicals from the body which keeps the risk of cell damage away

In addition, expression of ARX (an cell-specific transcription factor) was upregulated, whereas that of CHGA (a marker gene for pancreatic endocrine cells) was unchanged (Supplementary information, Fig