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Individuals on blood sugar medications or chemotherapy should discuss alpha lipoic acid and antioxidant supplements with a clinician

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We have focused on the well-known and potential role of therapeutic and toxic metabolites in the efficacy and safety of VPA in this narrative review, but we have not analyzed clinical randomized trials of the efficacy of valproates, including VPA and its salts

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53 However, the particular organism most relevant to this discussion is tropheryma whipplei