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While cortisol is an essential hormone necessary to sustain life, too much (or too little) of it can wreak havoc on bodily systems

Eli Lilly and Co., the drugs maker who paid for the research, has asked the Food and Drug Administration to expand use of the drug to treat moderate to severe sleep apnea, in which people stop and start breathing during sleep, a spokesperson said Friday

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As a result, half of patients stop within one year and 70 percent within two

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Therefore, GIP might increase metabolic flexibility by enabling increased fat utilisation in the fasting state and reducing fat availability in the postprandial state [24 25]