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In both studies, from a mean baseline body weight of 96.7 kg, and 85.6 kg, respectively, after randomization there were corresponding mean reductions of 1.4 kg, and 1.6 kg in the SYMLIN treatment group compared to mean increases of +0.3 kg, and +0.1 kg in the placebo treatment group
PMID 28176899
How GLP-1s May Affect Your Thyroid Results If you check your thyroid levels while taking a GLP-1, be aware of two key interactions: Changes in TSH Due to Weight Loss: Significant weight loss can lower your Thyroid Stimulating Hormone (TSH) levels
They mimic the actions of the endogenous incretin hormone GLP-1 that is released by the gut after eating
GLP-1 therapy may be appropriate for adults with: Treatment decisions should always be individualized after reviewing medical history, laboratory data, current medications, and overall health goals