Tirzepatide generally produces greater average weight loss in clinical trials, with the SURMOUNT-1 trial showing up to 22.5% body weight reduction at the highest dose compared to semaglutide roughly 15-17% in comparable trials
Journal of Bone and Mineral Research, 35, 13631374
But we need to, I need to, make sure that the oxidative stress is low enough for the body to respond to the hormones we can about to prescribe them
Sometimes, patients have such severe constipation that they have to stop taking tirzepatide
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