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Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus

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It is also listed under Section S2 of the WADA Prohibited List as a growth hormone-releasing factor, banned at all times, both in and out of competition, for athletes subject to anti-doping codes

This occurs because the underlying biological drivers of obesity, hormonal setpoints, metabolic adaptation, and appetite regulation, reassert themselves once the pharmacological intervention is removed