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The analysis is based on results from the STEP 1 trial, published in 2021 in the New England Journal of Medicine , which showed the 2.4 mg dosage of semaglutide approved by the FDA for the treatment of obesity reduced body weight by an average of 14.9% along with reductions in several cardiovascular risk factors such as blood pressure and lipids

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From bed to bench and back: Tnf-, Il-23/Il-17a, and Jak-dependent inflammation in the pathogenesis of psoriatic synovitis