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Description

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It discusses the pathophysiology of APAP metabolism, where the production of the toxic metabolite N-acetyl-p-benzoquinone imine (NAPQI) leads to hepatotoxicity when consumed in excessive doses

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Am J Physiol Endocrinol Metab 278:E405412 Lyons J, Rauh-Pfeiffer A, Yu YM, Lu XM, Zurakowski D, Tompkins RG, Ajami AM, Young VR, Castillo L (2000) Blood glutathione synthesis rates in healthy adults receiving a sulfur amino acid-free diet

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Science 330 , 13401344 (2010)

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